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For puzzling childhood immune disorder, gene research opens door to first...

A new genomics study, led by the Center for Applied Genomics at The Children's Hospital of Philadelphia, sets the stage for the first predictive diagnostic test in a serious immunodeficiency disease in...

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Orthopaedic surgeons see epidemic of thumb arthritis

(Medical Xpress) -- As baby boomers age, orthopaedic surgeons are seeing more and more patients, especially women, who suffer from debilitating arthritis of the thumb.

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Better understanding arthritis

Better arthritis treatment could be one step closer with research showing muscle inflammation outside joints as much to blame for discomfort and poor mobility in sufferers as inflammation of the joint...

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Even after Lyme disease is gone, its remains may perpetuate inflammation

(Medical Xpress) -- Non-infectious proteins of the species of bacteria that causes Lyme disease can remain in the body for a long time after antibiotic therapy, and are capable of causing an...

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New animal model for rheumatoid arthritis

Researchers at Northwestern University Feinberg School of Medicine have created the first animal model that spontaneously develops rheumatoid arthritis (RA) and is predisposed towards atherosclerosis,...

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Using antibodies against immune deficiency

Early, intensive therapy with a biotechnologically produced medication can provide significantly faster pain relief for patients with rheumatic joint inflammation. Damage to joints can also be reduced...

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'Humanized' mice advance study of rheumatoid arthritis

Researchers at Northwestern University Feinberg School of Medicine have developed the first animal model that duplicates the human response in rheumatoid arthritis (RA), an important step that may...

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Scientists step up hunt for bacterial genes tied to Lyme disease

Investigators at The University of Texas Health Science Center at Houston (UTHealth) have accelerated the search for the bacterial genes that make the Lyme disease bacterium so invasive and persistent....

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Xeljanz approved for rheumatoid arthritis

(HealthDay)—Xeljanz (tofacitinib) has been approved by the U.S. Food and Drug Administration to treat symptoms of rheumatoid arthritis (RA) among people who can't tolerate, or haven't been helped by,...

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Research finds new therapy options for children with severe juvenile...

Systemic juvenile idiopathic arthritis (SJIA) has long been considered a therapeutic orphan. Until now, the principal effective treatment has been high-dose steroids (prednisone) which are accompanied...

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Gout study offers genetic insight into 'disease of kings'

Scientists have shed light on why some people are more susceptible to gout than others. A study has identified 18 new genetic variations that increase levels of uric acid in the blood, which is the...

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Scientists improve arthritis treatments: Rheumatism patients can hope for a...

Together with colleagues from the international rheumatic diseases research community, scientists of the Charité – Universitätsmedizin Berlin have presented a new therapy approach for the treatment of...

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Ultrasound model IDs residual joint inflammation in RA

(HealthDay)—A model including ultrasound (US) assessment of the wrist, metacarpophalangeal (MCP), ankle, and metatarsophalangeal (MTP) joints is highly sensitive for detecting B-mode and Doppler joint...

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Experimental compound dramatically reduces joint inflammation

An experimental compound synthesized and developed by scientists from the Florida campus of The Scripps Research Institute (TSRI) has the capacity to significantly reduce joint inflammation in animal...

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Regular exercise beneficial in suppressing inflammation in rheumatic disease

Research findings presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) suggest that exercise transiently suppresses local and systemic inflammation, reinforcing the...

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Scientists find new mechanism by which cell signaling pathway contributes to...

A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the...

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Standard heart disease risk tools underrate danger in rheumatoid arthritis

Heart disease risk assessment tools commonly used by physicians often underestimate the cardiovascular disease danger faced by rheumatoid arthritis patients, a Mayo Clinic study has found. Inflammation...

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Researchers say tart cherries have 'the highest anti-inflammatory content of...

Tart cherries may help reduce chronic inflammation, especially for the millions of Americans suffering from debilitating joint pain and arthritis, according to new research from Oregon Health &...

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Studies explore racial disparities in IBD symptoms and therapy

Three separate studies presented today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas help to advance understanding of the differences between African...

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Master switch discovery could provide road map for treatment of arthritis and...

(Medical Xpress)—Scientists trying to create drugs to treat chronic inflammation in diseases like arthritis now have a new culprit known MMP2. New University of British Columbia research shows that...

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